A Mathematical Model for Zika Virus Infection and Microcephaly Risk Considering Sexual and Vertical Transmission

We establish a compartmental model for Zika virus disease transmission, with particular attention paid to microcephaly, the main threat of disease. To this end, we consider separate microcephaly-related compartments affected infants, as well role asymptomatic carriers, influence seasonality and transmission through sexual contact. determine basic reproduction number corresponding time-dependent time-constant study dependence value on mosquito-related parameters. In addition, demonstrate global stability disease-free periodic solution if R0<1, whereas persists when R0>1. fit our data from Colombia between 2015 2017 case study. The fitting is used figure out how affects cases among women microcephaly cases. Our sensitivity analyses conclude that most effective ways prevent Zika-related are preventing mosquito bites controlling populations, providing protection during